Slay the Spire 2 Card Guide

Mayhem

At the start of your turn, play the top card of your Draw Pile.

Character
Colorless
Type
Power
Cost
2
Rarity
Rare

Should You Pick Mayhem?

This card becomes valuable when your run already supports its mechanic. Without the proper synergy density, it can slow down early deck development.

When to Pick

  • When your build already supports this mechanic
  • When you need scaling damage
  • When the card fits your draft direction

When to Skip

  • When your deck lacks synergy support
  • When it slows early combat
  • When it competes with stronger scaling cards

Builds That Use Mayhem

poison exhaust attack-combo

Related Relics & Potions

Relics that enhance this card Potions that support this strategy

Mayhem FAQ

Is Mayhem a good card in Slay the Spire 2?

It depends on your deck direction. Cards are strongest when their mechanic is supported by relics and other cards.